Renier J. Brentjens : rechercher sur Z-Library

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1

Toxicity and management in CAR T-cell therapy

Bonifant, Challice L, Jackson, Hollie J, Brentjens, Renier J, Curran, Kevin J

Journal:

Molecular Therapy — Oncolytics

Année:

2016

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2016

2

Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRζ /CD28 receptor

Maher, John, Brentjens, Renier J., Gunset, Gertrude, Rivière, Isabelle, Sadelain, Michel

Journal:

Nature Biotechnology

Année:

2002

Langue:

english

Fichier:

PDF, 1.76 MB

english, 2002

3

How do CARs work?

Davila, Marco L., Brentjens, Renier, Wang, Xiuyan, Rivière, Isabelle, Sadelain, Michel

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 783 KB

english, 2012

4

Driving CAR T-cells forward

Jackson, Hollie J., Rafiq, Sarwish, Brentjens, Renier J.

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Année:

2016

Langue:

english

Fichier:

PDF, 617 KB

english, 2016

5

Emerging Role of CAR T Cells in Non-Hodgkin's Lymphoma

Avanzi, Mauro P., Brentjens, Renier J.

Journal:

Journal of the National Comprehensive Cancer Network

Année:

2017

Langue:

english

Fichier:

PDF, 223 KB

english, 2017

6

Early experience using salvage radiotherapy for relapsed/refractory nonâHodgkin lymphomas after CD19 chimericÂ antigen receptor (CAR)Â T cell therapy

Imber, Brandon S., Sadelain, Michel, DeSelm, Carl, Batlevi, Connie, Brentjens, Renier J., Dahi, Parastoo B., Giralt, Sergio, Park, Jae H., Sauter, Craig, Scordo, Michael, Shah, Gunjan, Perales, Miguel

Journal:

British Journal of Haematology

Année:

2020

Fichier:

PDF, 650 KB

2020

7

The promise and potential pitfalls of chimeric antigen receptors

Michel Sadelain, Renier Brentjens, Isabelle Rivière

Journal:

Current Opinion in Immunology

Année:

2009

Langue:

english

Fichier:

PDF, 194 KB

english, 2009

8

Eradication of systemic B-cell tumors by genetically targeted human T lymphocytes co-stimulated by CD80 and interleukin-15

Brentjens, Renier J., Latouche, Jean-Baptiste, Santos, Elmer, Marti, Francesc, Gong, Michael C., Lyddane, Clay, King, Philip D., Larson, Steven, Weiss, Mark, Rivière, Isabelle

Journal:

Nature Medicine

Année:

2003

Langue:

english

Fichier:

PDF, 298 KB

english, 2003

9

Chimeric antigen receptors for T cell immunotherapy: current understanding and future directions

Kevin J. Curran, Hollie J. Pegram, Renier J. Brentjens

Journal:

The Journal of Gene Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 258 KB

english, 2012

10

NK-92 cells engineered with anti-CD33 chimeric antigen receptors (CAR) for the treatment of Acute Myeloid Leukemia (AML)

Rafiq, Sarwish, Purdon, Terence J., Schultz, Liora, Klingemann, Hans, Brentjens, Renier J.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 264 KB

english, 2015

11

The future of cancer treatment: immunomodulation, CARs and combination immunotherapy

Khalil, Danny N., Smith, Eric L., Brentjens, Renier J., Wolchok, Jedd D.

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Année:

2016

Langue:

english

Fichier:

PDF, 646 KB

english, 2016

12

Review: Current clinical applications of chimeric antigen receptor (CAR) modified T cells

Geyer, Mark B., Brentjens, Renier J.

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 489 KB

english, 2016

13

393. Engineering Armored T Cell Receptor-Mimic (TCRm) Chimeric Antigen Receptor (CAR) T Cells Specific for the Intracellular Protein Wilms Tumor 1 (WT1) for Treatment of Hematologic and Solid Malignancies

Rafiq, Sarwish, Purdon, Terence, Dao, Tao, Liu, Chen, Scheinberg, David, Brentjens, Renier J.

Journal:

Molecular Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 335 KB

english, 2016

14

Armored CAR T cells enhance antitumor efficacy and overcome the tumor microenvironment

Yeku, Oladapo O., Purdon, Terence J., Koneru, Mythili, Spriggs, David, Brentjens, Renier J.

Journal:

Scientific Reports

Année:

2017

Langue:

english

Fichier:

PDF, 3.77 MB

english, 2017

15

Cytokine Release Syndrome Grade is a Predictive Marker for Infections in Relapsed or Refractory B-cell All Patients Treated with CAR T Cells

Park, Jae H, Romero, F Andres, Taur, Ying, Sadelain, Michel, Brentjens, Renier J, Hohl, Tobias M, Seo, Susan K

Journal:

Clinical Infectious Diseases

Année:

2018

Langue:

english

Fichier:

PDF, 634 KB

english, 2018

16

CAR T‐cell therapy: Full speed ahead

Sermer, David, Brentjens, Renier

Journal:

Hematological Oncology

Année:

2019

Langue:

english

Fichier:

PDF, 349 KB

english, 2019

17

Engineering strategies to overcome the current roadblocks in CAR T cell therapy

Rafiq, Sarwish, Hackett, Christopher S., Brentjens, Renier J.

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Année:

2019

Fichier:

PDF, 4.70 MB

2019

18

Novel approaches to the immunotherapy of B-cell malignancies: An update

Renier J. Brentjens

Journal:

Current Hematologic Malignancy Reports

Année:

2006

Langue:

english

Fichier:

PDF, 104 KB

english, 2006

19

Novel approaches to immunotherapy for B-cell malignancies

Renier J. Brentjens

Journal:

Current Oncology Reports

Année:

2004

Langue:

english

Fichier:

PDF, 364 KB

english, 2004

20

Sensitive in vivo imaging of T cells using a membrane-bound Gaussia princeps luciferase

Santos, Elmer B, Yeh, Raymond, Lee, James, Nikhamin, Yan, Punzalan, Blesida, Punzalan, Blesserene, Perle, Krista La, Larson, Steven M, Sadelain, Michel, Brentjens, Renier J

Journal:

Nature Medicine

Année:

2009

Langue:

english

Fichier:

PDF, 757 KB

english, 2009

21

T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection

Stephan, Matthias T, Ponomarev, Vladimir, Brentjens, Renier J, Chang, Alex H, Dobrenkov, Konstantin V, Heller, Glenn, Sadelain, Michel

Journal:

Nature Medicine

Année:

2007

Langue:

english

Fichier:

PDF, 977 KB

english, 2007

22

Targeting tumours with genetically enhanced T lymphocytes

Sadelain, Michel, Rivière, Isabelle, Brentjens, Renier

Journal:

Nature Reviews Cancer

Année:

2003

Langue:

english

Fichier:

PDF, 4.04 MB

english, 2003

23

Haemophilus ducreyi adheres to human keratinocytes

Renier J. Brentjens, Stanley M. Spinola, Anthony A. Campagnari

Journal:

Microbial Pathogenesis

Année:

1994

Fichier:

PDF, 226 KB

1994

24

Chimeric Antigen Receptor Therapy for Chronic Lymphocytic Leukemia

Davila, Marco L., Brentjens, Renier

Journal:

Hematology/Oncology Clinics of North America

Année:

2013

Langue:

english

Fichier:

PDF, 654 KB

english, 2013

25

Engineered Human Embryonic Stem Cell-Derived Lymphocytes to Study In Vivo Trafficking and Immunotherapy

Knorr, David A., Bock, Allison, Brentjens, Renier J., Kaufman, Dan S.

Journal:

Stem Cells and Development

Année:

2013

Langue:

english

Fichier:

PDF, 909 KB

english, 2013

26

Chimeric antigen receptors for the adoptive T cell therapy of hematologic malignancies

Davila, Marco L., Bouhassira, Diana C. G., Park, Jae H., Curran, Kevin J., Smith, Eric L., Pegram, Hollie J., Brentjens, Renier

Journal:

International Journal of Hematology

Année:

2014

Langue:

english

Fichier:

PDF, 421 KB

english, 2014

27

Cellular Therapies in Acute Lymphoblastic Leukemia

Park, Jae H., Sauter, Craig, Brentjens, Renier

Journal:

Hematology/Oncology Clinics of North America

Année:

2011

Langue:

english

Fichier:

PDF, 149 KB

english, 2011

28

Clinical Implementation of a Novel High-Throughput Screen of Primary Leukemia Cells to Personalize Therapy for Relapsed/Refractory Acute Myeloid Leukemia (AML)

Shum, David, Heaney, Mark L., Brentjens, Renier J., Maslak, Peter G., Jurcic, Joseph G., Djaballah, Hakim, Frattini, Mark G.

Journal:

Clinical Lymphoma Myeloma and Leukemia

Année:

2013

Langue:

english

Fichier:

PDF, 122 KB

english, 2013

29

ISLET CELL TUMORS OF THE PANCREAS

Brentjens, Renier, Saltz, Leonard

Journal:

Surgical Clinics

Année:

2001

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2001

30

Acute myeloid leukemia arising from a donor derived premalignant hematopoietic clone: A possible mechanism for the origin of leukemia in donor cells

Dickson, Mark A., Papadopoulos, Esperanza B., Hedvat, Cyrus V., Jhanwar, Suresh C., Brentjens, Renier J.

Journal:

Leukemia Research Reports

Année:

2014

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2014

31

T-Cell Immunotherapy: Looking Forward

Corrigan-Curay, Jacqueline, Kiem, Hans-Peter, Baltimore, David, O'Reilly, Marina, Brentjens, Renier J, Cooper, Laurence, Forman, Stephen, Gottschalk, Stephen, Greenberg, Philip, Junghans, Richard, Hes

Journal:

Molecular Therapy

Année:

2014

Langue:

english

Fichier:

PDF, 379 KB

english, 2014

32

Response

Brentjens, Renier, Riviere, Isabelle, Sadelain, Michel

Journal:

Human Gene Therapy

Année:

2008

Langue:

english

Fichier:

PDF, 48 KB

english, 2008

33

The Warburg Effect Confers Adverse Outcome in Chronic Lymphocytic Leukemia

Gardner, Jeffrey R., Devlin, Sean M., Knapp, Kristina, Bauli, Francesco, Patel, Minal, Lamanna, Nicole, Frattini, Mark G., Brentjens, Renier, Maslak, Peter, Jurcic, Joseph G., Weiss, Mark A., Abdel-Wa

Journal:

Clinical Lymphoma Myeloma and Leukemia

Année:

2014

Langue:

english

Fichier:

PDF, 132 KB

english, 2014

34

Targeting the Cell Cycle Regulated Cdc7 Kinase Pathway as a Novel Therapeutic Approach for Hematologic Malignancies

Santos, Ruth, Shum, David, Churchill, Michael, Mukherjee, Siddhartha, Brentjens, Renier J., Jurcic, Joseph G., Kelly, Thomas, Djaballah, Hakim, Frattini, Mark G.

Journal:

Clinical Lymphoma Myeloma and Leukemia

Année:

2014

Langue:

english

Fichier:

PDF, 88 KB

english, 2014

35

Multifactorial Optimization of Gammaretroviral Gene Transfer into Human T Lymphocytes for Clinical Application

Quintás-Cardama, Alfonso, Yeh, Raymond K., Hollyman, Daniel, Stefanski, Jolanta, Taylor, Clare, Nikhamin, Yan, Imperato, Gavin, Sadelain, Michel, Rivière, Isabelle, Brentjens, Renier J.

Journal:

Human Gene Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 142 KB

english, 2007

36

Enhancing Antitumor Efficacy of Chimeric Antigen Receptor T Cells Through Constitutive CD40L Expression

Curran, Kevin J, Seinstra, Beatrijs A, Nikhamin, Yan, Yeh, Raymond, Usachenko, Yelena, van Leeuwen, Dayenne G, Purdon, Terence, Pegram, Hollie J, Brentjens, Renier J

Journal:

Molecular Therapy

Année:

2015

Langue:

english

Fichier:

PDF, 2.09 MB

english, 2015

37

CD28z CARs and Armored CARs

Pegram, Hollie J., Park, Jae H., Brentjens, Renier J.

Journal:

The Cancer Journal

Année:

2014

Langue:

english

Fichier:

PDF, 4.67 MB

english, 2014

38

Treatment of Chronic Lymphocytic Leukemia With Genetically Targeted Autologous T Cells: Case Report of an Unforeseen Adverse Event in a Phase I Clinical Trial

Brentjens, Renier, Yeh, Raymond, Bernal, Yvette, Riviere, Isabelle, Sadelain, Michel

Journal:

Molecular Therapy

Année:

2010

Langue:

english

Fichier:

PDF, 199 KB

english, 2010

39

IL-12 secreting tumor-targeted chimeric antigen receptor T cells eradicate ovarian tumors in vivo

Koneru, Mythili, Purdon, Terence J., Spriggs, David, Koneru, Susmith, Brentjens, Renier J.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.77 MB

english, 2015

40

CAR therapy for hematological cancers: can success seen in the treatment of B-cell acute lymphoblastic leukemia be applied to other hematological malignancies?

Pegram, Hollie J, Smith, Eric L, Rafiq, Sarwish, Brentjens, Renier J

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.62 MB

english, 2015

41

[Advances in Pharmacology] Treatment of Leukemia and Lymphoma Volume 51 || Somatic Cell Engineering and the Immunotherapy of Leukemias and Lymphomas

Brentjens, Renier J.

Année:

2004

Langue:

english

Fichier:

PDF, 196 KB

english, 2004

42

CARs on Track in the Clinic

Kohn, Donald B, Dotti, Gianpietro, Brentjens, Renier, Savoldo, Barbara, Jensen, Michael, Cooper, Laurence JN, June, Carl H, Rosenberg, Steven, Sadelain, Michel, Heslop, Helen E

Journal:

Molecular Therapy

Année:

2011

Langue:

english

Fichier:

PDF, 262 KB

english, 2011

43

Novel immunotherapies in lymphoid malignancies

Batlevi, Connie Lee, Matsuki, Eri, Brentjens, Renier J., Younes, Anas

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Année:

2015

Langue:

english

Fichier:

PDF, 555 KB

english, 2015

44

The future of cancer treatment: immunomodulation, CARs and combination immunotherapy

Khalil, Danny N., Smith, Eric L., Brentjens, Renier J., Wolchok, Jedd D.

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Année:

2016

Fichier:

PDF, 63 KB

2016

45

Medical management of side effects related to CAR T cell therapy in hematologic malignancies

Namuduri, Manjusha, Brentjens, Renier J

Journal:

Expert Review of Hematology

Année:

2016

Langue:

english

Fichier:

PDF, 353 KB

english, 2016

46

A phase I clinical trial of adoptive T cell therapy using IL-12 secreting MUC-16ecto directed chimeric antigen receptors for recurrent ovarian cancer

Koneru, Mythili, O’Cearbhaill, Roisin, Pendharkar, Swati, Spriggs, David R, Brentjens, Renier J

Journal:

Journal of Translational Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 675 KB

english, 2015

47

CD19-Targeted T Cells for Hematologic Malignancies

Davila, Marco L., Sauter, Craig, Brentjens, Renier

Journal:

The Cancer Journal

Année:

2015

Langue:

english

Fichier:

PDF, 186 KB

english, 2015

48

Phase I trial: CD19-Targeted CAR T-Cells in Patients with Residual CLL Following Initial Purine Analog-Based Therapy

Geyer, Mark, Park, Jae, Rivière, Isabelle, Senechal, Brigitte, Hsu, Meier, Wang, Xiuyan, Purdon, Terence, Sadelain, Michel, Brentjens, Renier

Journal:

Clinical Lymphoma Myeloma and Leukemia

Année:

2016

Langue:

english

Fichier:

PDF, 238 KB

english, 2016

49

NIH Public Access

Brentjens, Renier, Davila, Marco L, Riviere, Isabelle, Park, Jae, Cowell, Lindsay G, Bartido, Shirley, Stefanski, Jolanta, Taylor, Clare, Borquez-ojeda, Oriana, Qu, Jinrong, Wasielewska, Teresa, He, Q

Année:

2013

Langue:

english

Fichier:

PDF, 1.96 MB

english, 2013

50

408. CD19-Targeted CAR T Cells “Armored” To Secrete IL-12 Demonstrate Superior Efficacy Against B Cell Acute Lymphoblastic Leukemia and Resist Treg Immunosuppression

Chang, Peter S., Lee, James C., Koneru, Mythili, Brentjens, Renier J.

Journal:

Molecular Therapy

Année:

2015

Langue:

english

Fichier:

PDF, 661 KB

english, 2015